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Here, we display that conolidine, a all-natural analgesic alkaloid Utilized in conventional Chinese medicine, targets ACKR3, therefore delivering supplemental evidence of the correlation between ACKR3 and suffering modulation … Read More

While the opiate receptor relies on G protein coupling for signal transduction, this receptor was found to employ arrestin activation for internalization of the receptor. Usually, the receptor promoted no other signaling casca… Read More